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Slowdown will happen if you have the following:

- Windows XP SP3
- installed .NET Framework 4

Here is what I found to fix the problem:

Solution A

1) Run cmd.exe from Start > Run
2) Type cd
3) Type cd C:WindowsMicrosoft.NETFrameworkv4.0.30319
4) Type NGEN executequeueditems and press Enter
5) It will take about 10minutes depending upon system speed. After the process is complete, the following prompt will appear in the command prompt C:WindowsMicrosoft.NETFrameworkv4.0.30319
6) Type exit to close the command prompt.

After performing these steps, your computer will boot up at usual speed.

Solution B 

Microsoft hasnt provided an official fix yet, but here is the fix that solves this slow system startup.
DOWNLOAD FIX TOOL

Just download the fix tool, unpack it and run. It will probably take few minutes to process.

From : RejZoR